| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IF/ICC, ELISA | 60 | Human, Mouse |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IF/ICC=1:50-300 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | TCP1α/CCTα Rabbit Polyclonal Antibody detects endogenous levels of TCP1α/CCTα protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
TCP1α also known as T complex 1, CCTα is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT). TCP1α plays a vital role in the proper folding of cytosolic proteins, particularly actins and tubulins, which are fundamental for maintaining cellular structure and function. TCP1α was first identified in mice with tail-less and embryonic lethal phenotypes, demonstrating its importance in critical developmental processes. Homologous sequences of TCP1 have been identified across various species, indicating evolutionary conservation and significance in cellular biology. TCP1′s function as a molecular chaperone for actin and tubulin in both mammalian cells and yeast emphasizes its essential role in ensuring cytoskeletal framework integrity, which is crucial for numerous cellular processes, including motility, division, and intracellular transport. |
| Product Image Gallery | |
 Western blot analysis of extracts on 293T, Jurkat cells, using TCP1α/CCTα Rabbit Polyclonal Antibody (EAB14025) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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