| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Monoclonal | WB, IHC-P, IF/ICC | 42 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:1000-5000 IHC-P=1:100-500 IF/ICC=1:100-500 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | SCD Rabbit Monoclonal Antibody detects endogenous levels of SCD protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
SCD is an enzyme involved in fatty acid biosynthesis, primarily the synthesis of oleic acid. SCD belongs to the fatty acid desaturase family and is an integral membrane protein located in the endoplasmic reticulum. SCD plays a significant role in the secretion of triacylglycerols and phospholipids, as well as in regulating cellular cholesterol levels. SCD undergoes rapid turnover within cells, making SCD an excellent model for studying the selective degradation of short-lived endoplasmic reticulum proteins. SCD expression increases in cells differentiating into adipocytes and in certain tumor cell lines, highlighting SCD′s importance in metabolic processes and potential implications in cancer biology. SCD gene family exhibits variability across species due to gene duplication events, and SCD expression is influenced by dietary levels of unsaturated fatty acids, further underscoring SCD′s relevance in both physiological and pathological contexts. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, NIH/3T3 cells, using SCD Rabbit Monoclonal Antibody (EAB22164) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
Predicted band size: 42 kDa; Observed band size: 37 kDa |
