| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF/ICC, ELISA | 11 | Human, Mouse |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IHC-P=1:50-300 IF/ICC=1:50-300 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | S100A8 Rabbit Polyclonal Antibody detects endogenous levels of S100A8 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
S100A8 also known as Calgranulin A, MRP8 is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100A8 plays a crucial role in the immune response, particularly in inflammation and tissue repair. S100A8 is primarily expressed in macrophages and epithelial cells, where S100A8 is involved in the regulation of calcium homeostasis and the modulation of cellular activities during inflammatory processes. S100A8 presence in these cells is significant as S100A8 not only serves as a marker for inflammatory conditions but also participates in the recruitment and activation of immune cells, thereby influencing the overall immune response. Additionally, S100A8 has been implicated in various pathological conditions, including cancer and autoimmune diseases, making S100A8 a valuable target for research and therapeutic applications. |
| Product Image Gallery | |
 Western blot analysis of extracts on MCF7, THP-1 cells, using S100A8 Rabbit Polyclonal Antibody (EAB14811) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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