| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IF/ICC, ELISA | 42 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IF/ICC=1:50-300 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | PRMT1 Rabbit Polyclonal Antibody detects endogenous levels of PRMT1 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
PRMT1(Protein arginine methyltransferase 1) is a member of the protein arginine N-methyltransferase (PRMT) family. PRMT1 plays a crucial role in post-translational modification of RNA-binding proteins, essential for regulating gene expression and RNA processing. Located predominantly in the nucleus, PRMT1 is involved in methylation of arginine residues on target proteins, influencing function and interactions. PRMT1 interacts with Interleukin enhancer-binding factor 3 (ILF3) at its carboxy terminus, which modulates PRMT1 activity and highlights the importance of protein-protein interactions in cellular regulation. Alternative mRNA splicing of the PRMT gene results in three isoforms of PRMT1, all retaining enzymatic activity, underscoring the complexity and versatility in various biological contexts. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, A549 cells, using PRMT1 Rabbit Polyclonal Antibody (EAB13930) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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