| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF, ELISA | 41 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IHC-P=1:50-300 IF=1:50-300 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Cyclophilin 40/PPID Rabbit Polyclonal Antibody detects endogenous levels of Cyclophilin 40/PPID protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Cyclophilin 40 also known as, Cyclophilin D, CYP-40, PPID is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. Cyclophilin 40 plays a crucial role in protein folding and isomerization, specifically catalyzing the cis-trans isomerization of proline imidic peptide bonds in oligopeptides, which is essential for proper protein function and stability. Cyclophilin 40 is predominantly located in the cytoplasm, where Cyclophilin 40 interacts with various client proteins, including steroid hormone receptors, thereby influencing their activity and stability. Cyclophilin 40′s ability to modulate the function of these receptors highlights Cyclophilin 40′s importance in cellular signaling pathways and stress responses, making Cyclophilin 40 a significant target for research in areas such as cancer and autoimmune diseases. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, K562 cells, using Cyclophilin 40/PPID Rabbit Polyclonal Antibody (EAB13926) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
 Immunohistochemical analysis of paraffin-embedded Mouse brain tissue, using Cyclophilin 40/PPID Rabbit Polyclonal Antibody (EAB13926) at 1:100 dilution.
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