| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, ELISA | 53 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IHC-P=1:50-300 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | DUSP10/MKP5 Rabbit Polyclonal Antibody detects endogenous levels of DUSP10/MKP5 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
DUSP10(Dual specificity phosphatase 10) also known as MKP5 plays a crucial role in regulating mitogen-activated protein (MAP) kinase signaling pathways, which are essential for mediating cellular responses to a variety of stimuli. Specifically, DUSP10 dephosphorylates and inactivates p38 MAPK and SAPK/JNK, thereby modulating processes such as cell proliferation, apoptosis, and immune responses. DUSP10′s ability to regulate these pathways is vital for maintaining cellular homeostasis and preventing excessive inflammatory responses, which can lead to pathological conditions. DUSP10 is ubiquitously expressed and can be found in both cytoplasm and nucleus, highlighting DUSP10′s importance in various cellular contexts. |
| Product Image Gallery | |
 Western blot analysis of extracts on NIH/3T3 cells, using DUSP10/MKP5 Rabbit Polyclonal Antibody (EAB14134) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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