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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF, ELISA | 52 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 IHC-P=1:50-300 IF=1:50-300 |
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| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | HNF-4α/γ Rabbit Polyclonal Antibody detects endogenous levels of HNF-4α/γ protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
HNF-4α/γ(Hepatocyte nuclear factor 4α/γ ) also known as HNF4A/HNF4G is a transcription factor that belongs to the orphan nuclear receptor superfamily. HNF-4α/γ plays an essential role in regulating genes involved in glucose and lipid metabolism, making it a key player in maintaining metabolic homeostasis. Dysfunction of HNF-4 α is associated with several metabolic disorders, including diabetes and obesity, highlighting its significance in both basic and clinical research. Understanding HNF-4 α function can provide insights into therapeutic targets for metabolic conditions. HNF4γ along with HNF1α regulates this transcriptome. HNF4γ generates and maintains enhancers at the gastrointestinal-lineage genes as a pioneer factor and mediates castration resistance.
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| Product Image Gallery | |
 Western blot analysis of extracts on SW480, SKOV3 cells, using HNF4-α/γ Rabbit Polyclonal Antibody (EAB13904) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
 Immunohistochemical analysis of paraffin-embedded Rat kidney tissue, using HNF4α/γ Rabbit Polyclonal Antibody (EAB13904) at 1:100 dilution.
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