| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF/ICC, ELISA | 153 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IHC-P=1:50-300 IF/ICC=1:50-300 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | VEGFR3/FLT4 Rabbit Polyclonal Antibody detects endogenous levels of VEGFR3/FLT4 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
FLT4 also known as VEGFR-3 is a receptor tyrosine kinase that plays a crucial role in lymphangiogenesis and lymphatic system development. FLT4 is primarily located on endothelial cell surfaces, where FLT4 regulates lymphatic vessel formation and maintenance. Proper FLT4 function is essential for fluid homeostasis and immune response, facilitating immune cell transport and interstitial fluid drainage. Dysregulation of FLT4 signaling has been implicated in various pathological conditions, including cancer metastasis and lymphedema, making FLT4 a significant therapeutic target. Seven immunoglobulin-like domains in FLT4′s structure contribute to high-affinity ligand binding, similar to related receptors Flt-1 and Flk-1, which interact with vascular endothelial growth factors. |
| Product Image Gallery | |
 Western blot analysis of extracts on 293T, Mouse kidney cells, using VEGFR3/FLT4 Rabbit Polyclonal Antibody (EAB11973) at 1:500 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
Predicted band size: 153 kDa; Observed band size: 170 kDa  Immunohistochemical analysis of paraffin-embedded Human placenta tissue, using VEGFR3/FLT4 Rabbit Polyclonal Antibody (EAB11973) at 1:200 dilution.
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