| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF/ICC, ELISA | 53 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IHC-P=1:50-300 IF/ICC=1:50-300 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | ETV6/TEL Rabbit Polyclonal Antibody detects endogenous levels of ETV6/TEL protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
TEL also known as ETV6 is an ETS family transcription factor. TEL plays a crucial role in hematopoiesis and is involved in the regulation of gene expression during blood cell development. TEL protein′s importance is underscored by involvement in specific chromosomal translocations associated with human leukemias and sarcomas, which can lead to the disruption of normal cellular functions and contribute to oncogenesis. TEL protein′s ability to bind DNA is facilitated by a highly conserved carboxy terminal domain that contains a sequence related to the SV40 large T antigen nuclear localization signal, allowing TEL to interact with specific DNA motifs, including the 5′-GGAA-3′ element. This interaction is vital for the transcriptional regulation of target genes, making TEL protein a significant player in both normal cellular processes and disease states. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, HepG2, Jurkat cells, using ETV6/TEL Rabbit Polyclonal Antibody (EAB13861) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
 Immunohistochemical analysis of paraffin-embedded Human colon cancer tissue, using ETV6/TEL Rabbit Polyclonal Antibody (EAB13861) at 1:200 dilution.
 Immunofluorescence analysis of Hela cell, using ETV6/TEL Rabbit Polyclonal Antibody (EAB13861) at 1:200 dilution.
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