| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IF/ICC, ELISA | 55 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IF/ICC=1:50-300 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Phospho-EpoR (Tyr368) Rabbit Polyclonal Antibody detects endogenous levels of EpoR protein only when phosphorylated at Tyr368. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
EpoR(Erythropoietin receptor) is a member of the cytokine receptor family. EpoR is essential for initiating downstream signaling pathways that lead to cell proliferation and survival. EpoR shares significant structural similarities with the interleukin 2 receptor beta-chain subunit, particularly in the conserved box 1 and box 2 domains of their cytoplasmic regions, which are critical for receptor function. These conserved domains facilitate the coupling of ligand binding to the induction of tyrosine phosphorylation, a key step in signal transduction. Additionally, the membrane proximal region of EpoR is vital for the recruitment of Janus kinase 2 (JAK2), further underscoring the importance of EpoR′s structure in functional role. |
| Product Image Gallery | |
 Western blot analysis of extracts on K562 cells, using Phospho-EpoR (Tyr368) Rabbit Polyclonal Antibody (EAB13857) at 1:1000 dilution. The lane on the left is blocked with the phospho peptide.
 Immunofluorescence analysis of HepG2 cell, using Phospho-EpoR (Tyr368) Rabbit Polyclonal Antibody (EAB13857) at 1:100 dilution.
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