| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF/ICC, ELISA | 41 | Human, Mouse |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IHC-P=1:50-300 IF/ICC=1:50-300 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Phospho-CXCR2/IL8RB (Ser347) Rabbit Polyclonal Antibody detects endogenous levels of CXCR2/IL8RB protein only when phosphorylated at Ser347. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
CXCR2 also known as IL8Rβ, CD182, IL8RB is a member of the G-protein-coupled receptor family. CXCR2 is a receptor for interleukin 8 (IL8).plays a crucial role in mediating inflammatory responses by acting as a receptor for interleukin-8 (IL-8), a potent chemotactic factor for neutrophils. This receptor is predominantly expressed on neutrophils, with lower levels found on monocytes and certain myeloid cell lines, which underscores its importance in the immune response and inflammation. Notably, CXCR2 is part of the seven transmembrane domain rhodopsin superfamily of receptors, which are essential for G protein-coupled signal transduction. The interaction of CXCR2 with IL8 not only facilitates neutrophil chemotaxis but also enhances their activation, making CXCR2 a key player in the pathophysiology of various inflammatory diseases. |
| Product Image Gallery | |
 Western blot analysis of extracts on NIH/3T3 cells treated with PMA, using Phospho-CXCR2/IL8RB (Ser347) Rabbit Polyclonal Antibody (EAB14207) at 1:1000 dilution. The lane on the left is blocked with the phospho peptide.
Predicted band size: 41 kDa; Observed band size: 48 kDa  Immunohistochemistry analysis of paraffin-embedded Human breast carcinoma tissue, using Phospho-CXCR2/IL8RB (Ser347) Rabbit Polyclonal Antibody (EAB14207) at 1:100 dilution.
 Immunofluorescence analysis of COS7 cell, using Phospho-CXCR2/IL8RB (Ser347) Rabbit Polyclonal Antibody (EAB14207) at 1:100 dilution.
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