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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P | 58 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 IHC-P=1:50-300 |
|
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | CYP1A1 Rabbit Polyclonal Antibody detects endogenous levels of CYP1A1 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
CYP1A1(Cytochrome P450 1A1) is a member of the cytochrome P450 superfamily of enzymes. CYP1A1 plays a crucial role in metabolizing diverse endogenous compounds, such as hormones and fatty acids, as well as xenobiotics, including drugs and environmental toxins. Proper functioning of CYP1A1 is vital for detoxifying harmful substances and maintaining metabolic homeostasis, making CYP1A1 an important target for studying drug metabolism and toxicology. CYP1A1 is primarily located in the endoplasmic reticulum of liver cells, where CYP1A1 catalyzes substrate oxidation, highlighting CYP1A1′s significance in hepatic metabolism. Understanding CYP1A1 expression and regulation can provide insights into individual variations in drug response and susceptibility to toxic compounds, underscoring CYP1A1′s importance in pharmacogenomics and personalized medicine. |
| Product Image Gallery | |
 Western blot analysis of extracts on MCF7, Mouse lvier cells, using CYP1A1 Rabbit Polyclonal Antibody (EAB13805) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
Predicted band size: 58 kDa; Observed band size: 63 kDa  Immunohistochemistry of paraffin-embedded Human liver cancer tissue, using CYP1A1/CYP1A2 Rabbit Polyclonal Antibody (EAB13805) at 1:100 dilution.
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