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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF, ELISA | 53 | Human, Mouse |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 IHC-P=1:50-300 IF=1:50-300 |
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| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | CPE Rabbit Polyclonal Antibody detects endogenous levels of CPE protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
CPE also known as CPH is a member of the M14 family of metallocarboxypeptidases. CPE plays a critical role in prohormone processing, specifically in the removal of C-terminal arginine or lysine residues following initial endoprotease cleavage, which is essential for the maturation of various peptide hormones. This enzymatic activity is particularly important in the processing of proinsulin, ensuring that insulin is produced in its active form, which is vital for glucose metabolism and overall energy homeostasis. Additionally, CPE is necessary for the proper development of photoreceptor synaptic terminals, facilitating normal signal transmission to the inner retina, thereby contributing to visual function. |
| Product Image Gallery | |
 Western blot analysis of extracts on K562, Mouse brain cells, using CPE Rabbit Polyclonal Antibody (EAB13774) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
 Immunohistochemical analysis of paraffin-embedded Rat brain tissue, using CPE Rabbit Polyclonal Antibody (EAB13774) at 1:100 dilution.
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