| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 83 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | COMP Rabbit Polyclonal Antibody detects endogenous levels of COMP protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
COMP also known as Thrombospondin 5, THBS5 is a noncollagenous extracellular matrix (ECM) protein. COMP is primarily located in the extracellular matrix of cartilage, tendon, and vascular smooth muscle, where COMP is developmentally regulated and localized to the chondrocyte territorial and interterritorial matrix. Proper localization of COMP is vital for binding to Collagen Types I, II, and IX in a zinc-dependent manner, which is important for the stability and organization of the extracellular matrix. Mutations in the COMP/THBS5 gene can lead to serious genetic disorders such as pseudoachondroplasia and multiple epiphyseal dysplasia, both of which are characterized by skeletal abnormalities and can result in significant health issues. |
| Product Image Gallery | |
 Western blot analysis of extracts on Jurkat cells, using COMP Rabbit Polyclonal Antibody (EAB13770) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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