| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF/ICC, ELISA | 52 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IHC-P=1:100-500 IF/ICC=1:100-500 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Clusterin Rabbit Polyclonal Antibody detects endogenous levels of Clusterin protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Clusterin also known as CLI, ApoJ, SGP2, SP-40, TRPM2 is a multifunctional secretory heterodimeric glycoprotein involved in immune regulation, cell adhesion, lipid transportation, tissue remodeling, membrane recycling, and cell-cell interactions. Within cells, Clusterin is predominantly localized in the extracellular matrix, where Clusterin plays a critical role in maintaining cellular homeostasis by inhibiting the complement system and preventing unwanted immune responses. Additionally, Clusterin is found in the cytoplasm and nucleus, where Clusterin is involved in regulating apoptosis, protecting cells from stress-induced damage, and facilitating intracellular signaling pathways. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, A549 cells, using Clusterin Rabbit Polyclonal Antibody (EAB13762) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
 Immunohistochemical analysis of paraffin-embedded Human amygdala tissue, using Clusterin Rabbit Polyclonal Antibody (EAB13762) at 1:400 dilution.
 Immunofluorescence analysis of Hela cell, using Clusterin Rabbit Polyclonal Antibody (EAB13762) at 1:200 dilution.
|
