| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 48 | Human, Mouse |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | CLN3 Rabbit Polyclonal Antibody detects endogenous levels of CLN3 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
CLN3 is a protein that is involved in lysosomal function. CLN3 plays a vital role in lysosomal function, potentially acting as a chaperone that assists in the proper folding and unfolding of other proteins, including subunit C of the ATP synthase complex. Mutations in CLN3 gene are linked to Batten disease, a recessively inherited neurodegenerative disorder characterized by lysosomal accumulation of hydrophobic materials, primarily affecting the ATP synthase subunit C. Batten disease represents the most prevalent form of a group of disorders known as neuronal ceroid lipofuscinoses (NCLs), with symptoms that include progressive vision loss, seizures, and psychomotor disturbances, underscoring the importance of CLN3 protein in maintaining cellular health and function. |
| Product Image Gallery | |
 Western blot analysis of extracts on MCF7, Mouse liver cells, using CLN3 Rabbit Polyclonal Antibody (EAB13760) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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