| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF/ICC, ELISA | 85 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IHC-P=1:50-300 IF/ICC=1:50-300 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Integrin β2 Rabbit Polyclonal Antibody detects endogenous levels of Integrin β2 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Integrin β2 also known as ITGB2, CD18 is an integrin beta chain, which combines with multiple different alpha chains to form different integrin heterodimers. Integrin β2 plays a crucial role in cell adhesion and signaling, functioning as a key component of integrin heterodimers that mediate interactions between cells and the extracellular matrix. Integrin β2 is primarily located on the cell surface, where Integrin β2 forms heterodimers with integrin α subunits, facilitating the binding of ligands such as fibronectin, collagen, and vitronectin. This binding is essential for various biological processes, including cell migration, immune response, and tissue repair. Proper localization of Integrin β2 at the cell membrane is vital for function, as such positioning allows for dynamic regulation of cell adhesion and signaling pathways that influence cellular behavior. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, Mouse lung cells, using Integrin β2 Rabbit Polyclonal Antibody (EAB13748) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
Predicted band size: 85 kDa; Observed band size: 95 kDa  Immunohistochemical analysis of paraffin-embedded Human oophoroma tissue, using Integrin β2 Rabbit Polyclonal Antibody (EAB13748) at 1:200 dilution.
 Immunofluorescence analysis of Hela cell, using Integrin β2 Rabbit Polyclonal Antibody (EAB13748) at 1:100 dilution.
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