| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 42 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | CCR2 Rabbit Polyclonal Antibody detects endogenous levels of CCR2 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
CCR2(C-C chemokine receptor type 2) also known as CD192, CKR2 is a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. CCR2 plays a crucial role in immune response by mediating chemotaxis of monocytes and T cells to sites of inflammation, which is vital for effective immune surveillance and response to pathogens. This 374 amino acid multi-pass membrane protein is expressed in two isoforms, CKR-2A and CKR-2B, both serving as receptors for various chemokines, including monocyte chemoattractant protein-1 (MCP-1) and MCP-3. Upon binding to these ligands, CCR2 influences intracellular calcium levels and initiates signal transduction pathways essential for migration and activation of immune cells. CCR2 receptor has been implicated in facilitating viral infections, highlighting a dual role in both immune response and potential pathogenesis. |
| Product Image Gallery | |
 Western blot analysis of extracts on HuvEc, NIH/3T3 cells, using CCR2 Rabbit Polyclonal Antibody (EAB13724) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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