Osteocalcin Rabbit Polyclonal Antibody
Catalog #:EAB13696
Host / Isotype Clonality Applications MW (kDa) Reactivity
Rabbit IgG Polyclonal WB, IF/ICC, ELISA 11 Human, Mouse, Rat
Application Key

WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry

Reactivity Key

H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Applications Dilutions
The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user.
WB(Westem Blotting)
IHC-P(Immunohistochemistry-Paraffin)
IF/ICC(Immunofluorescence/Immunocytochemistry)
ELISA(Enzyme-linked Immunosorbent Assay)
WB=1:500-2000 
IF/ICC=1:50-300
Product Information
Conjugate Unconjugate
Specificity Osteocalcin Rabbit Polyclonal Antibody detects endogenous levels of Osteocalcin protein.
Purification Affinity purification
Concentration 1mg/ml
Format Liquid
Formulation In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping Gel Pack
Storage Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
UniProt ID

P02818

Entrez Gene ID

632

Product Description

Osteocalcin also known as OCN, BGP, BGLAP is a highly abundant bone protein secreted by osteoblasts that regulates bone remodeling and energy metabolism. Osteocalcin plays a crucial role in bone metabolism and is primarily produced by osteoblasts. Osteocalcin binds to hydroxyapatite in a calcium-dependent manner, facilitating mineral deposition in the bone matrix. Osteocalcin expression in bone is particularly important during embryonic stage mineral deposition and remains one of the most abundant non-collagenous proteins in adult mineralized bone. Genetic variations at the osteocalcin locus on chromosome 1q have been linked to variations in postmenopausal bone mineral density, highlighting osteocalcin′s significance in osteoporosis susceptibility.

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For Research Use Only, Not For Diagnostic Or Therapeutic Procedures.
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