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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF, ELISA | 54 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 IHC-P=1:50-300 IF=1:50-300 |
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| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Cytokeratin 8 Rabbit Polyclonal Antibody detects endogenous levels of Cytokeratin 8 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Cytokeratin 8 also known as Keratin 8, CK8, KRT8 is a vital component of the cytoskeletal structure in epithelial cells. Cytokeratin 8 playing a crucial role in maintaining cellular integrity and providing mechanical support. Cytokeratin 8 is predominantly located in the cytoplasm of simple epithelial cells, where Cytokeratin 8 forms intermediate filaments that contribute to the overall architecture of the tissue. Cytokeratin 8 presence is particularly important in epithelial differentiation and tissue specialization, serving as a marker for various epithelial-derived tumors. Notably, abnormal Cytokeratin 8 expression has been associated with squamous cell carcinomas, indicating a potential role in tumor progression and malignancy. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, A549 cells, using Cytokeratin 8 Rabbit Polyclonal Antibody (EAB13554) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
 Immunohistochemistry analysis of paraffin-embedded Human kidney tissue, using Cytokeratin 8 Rabbit Polyclonal Antibody (EAB13554) at 1:100 dilution.
 Immunohistochemistry analysis of paraffin-embedded Human colon tissue, using Cytokeratin 8 Rabbit Polyclonal Antibody (EAB13554) at 1:100 dilution.
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