Integrin α2 Rabbit Polyclonal Antibody
Catalog #:EAB13552
Host / Isotype Clonality Applications MW (kDa) Reactivity
Rabbit IgG Polyclonal WB, IHC-P, IF, ELISA 129 Human, Mouse, Rat
Applications Dilutions
The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user.
WB=1:500-2000 
IHC-P=1:50-300 
IF=1:50-300 
Application Key

WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry

Reactivity Key

H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Information
Conjugate Unconjugate
Specificity Integrin α2 Rabbit Polyclonal Antibody detects endogenous levels of Integrin α2 protein.
Purification Affinity purification
Concentration 1mg/ml
Format Liquid
Formulation In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping Gel Pack
Storage Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
UniProt ID

P17301

Entrez Gene ID

3673

Product Description

Integrin α2 also known as ITGA2, CD49b plays a crucial role in mediating cell adhesion to collagen, which is essential for maintaining tissue integrity and facilitating communication between cells and the extracellular matrix. Integrin α2 is primarily located on the surface of platelets and various other cell types, where anti-Integrin α2 antibody (P1E6) can detect interactions with collagen fibers, promoting platelet aggregation and wound healing. The ability of Integrin α2 to bind collagen is vital for the formation of stable blood clots and the repair of damaged tissues, highlighting its importance in both hemostasis and tissue regeneration. Furthermore, Integrin α2 is involved in signaling pathways that regulate cell migration and proliferation, making Integrin α2 a key player in various physiological and pathological processes, including inflammation and cancer metastasis.

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For Research Use Only, Not For Diagnostic Or Therapeutic Procedures.
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