| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF/ICC, ELISA | 55 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IHC-P=1:50-300 IF/ICC=1:50-300 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | MMP-11 Rabbit Polyclonal Antibody detects endogenous levels of MMP-11 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
MMP-11 also known as STMY3 is a member of the matrix metalloproteinase (MMP) gene family. MMP-11 plays a crucial role in the remodeling of the extracellular matrix, which is vital for processes such as tissue repair, embryogenesis, and tumor progression. MMP-11 is predominantly expressed in stromal cells of breast carcinomas, where MMP-11 contributes to the malignancy of epithelial cells by facilitating the degradation of extracellular matrix components, thereby promoting tumor invasion and metastasis. The regulation of MMP-11 is complex, as MMP-11 expression can be influenced by various factors including cytokines and growth factors, making MMP-11 an important target for understanding cancer biology and developing therapeutic strategies. |
| Product Image Gallery | |
 Western blot analysis of extracts on A549 cells, using MMP-11 Rabbit Polyclonal Antibody (EAB13479) at 1:500 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
 Immunohistochemistry analysis of paraffin-embedded Human breast carcinoma tissue, using MMP-11 Rabbit Polyclonal Antibody (EAB13479) at 1:100 dilution.
 Immunofluorescence analysis of A549 cells, using MMP-11 Rabbit Polyclonal Antibody (EAB13479) at 1:200 dilution.
|
