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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 39 | Human, Mouse |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 |
|
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | HDAC11 Rabbit Polyclonal Antibody detects endogenous levels of HDAC11 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
HDAC11(Histone deacetylase 11) also known as HD11 is member of class IV histone deacetylases and plays a pivotal role in the regulation of gene expression by removing acetyl groups from histone proteins, leading to chromatin condensation and transcriptional repression. This enzymatic activity is crucial for various cellular processes, including differentiation, proliferation, and apoptosis, making HDAC11 a key player in maintaining cellular homeostasis and epigenetic regulation. Unlike other HDAC classes, HDAC11 possesses unique structural features that confer specific regulatory functions, including involvement in metabolic pathways and immune response modulation. HDAC11 expression levels are high in vital tissues such as the kidney, heart, brain, skeletal muscle, and testis, where HDAC11 influences tissue-specific gene expression and cellular functions. |
| Product Image Gallery | |
 Western blot analysis of extracts on HuvEc cells, using HDAC11 Rabbit Polyclonal Antibody (EAB13468) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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