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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, ELISA | 56 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 IHC-P=1:50-300 |
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| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Phospho-Rad18 (Ser403) Rabbit Polyclonal Antibody detects endogenous levels of Rad18 protein only when phosphorylated at Ser403. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Rad18 is highly similar to S. cerevisiae DNA damage repair protein Rad18. Rad18 plays a crucial role in post-replication repair of damaged DNA, which is vital for maintaining genomic stability and preventing mutations that could lead to cancer. Specifically, Rad18 is involved in recruiting ubiquitin-conjugating enzymes within the Rad6 pathway, facilitating modification of proteins essential for DNA repair processes. Rad18 interacts with other key proteins, such as Rad54, to ensure effective repair of chromosomal DNA. This interaction helps fill gaps in daughter strands during replication of damaged DNA, thereby preserving genetic material integrity. Rad18 is predominantly localized in the nucleus, where DNA damage response functions occur. |
| Product Image Gallery | |
 Western blot analysis of extracts on Raji cells treated with UV, using Phospho-Rad18 (Ser403) Rabbit Polyclonal Antibody (EAB13373) at 1:1000 dilution. The lane on the left is blocked with the phospho peptide.
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