| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 72 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | DNAJC2/MPP11 Rabbit Polyclonal Antibody detects endogenous levels of DNAJC2/MPP11 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
MPP11 also known as Zuotin-1, DNAJC2 is a member of the M-phase phosphoprotein (MPP) family. MPP11 plays a crucial role in cellular protein homeostasis as a ribosome-associated DnaJ molecular chaperone. MPP11 contains one J domain and two SANT domains, which are essential for assisting proper folding of nascent polypeptides and preventing protein aggregation. MPP11′s importance lies in its interaction with the HSP 70 chaperone machinery, where MPP11 stimulates ATP hydrolysis, facilitating the protein folding process. This interaction is vital for maintaining cellular function, especially under stress conditions, as MPP11 helps ensure proteins achieve correct conformation and function. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela cells, using DNAJC2/MPP11 Rabbit Polyclonal Antibody (EAB13279) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
Predicted band size: 72 kDa; Observed band size: 80 kDa |
