| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 22 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Claudin-11 Rabbit Polyclonal Antibody detects endogenous levels of Claudin-11 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Claudin-11 also known as CLDN11 is a member of the claudin family. Claudin-11 protein functions as a crucial component of tight junctions, essential for maintaining epithelial and endothelial barrier integrity. Tight junctions regulate paracellular transport, ensuring substances pass through spaces between cells in a controlled manner. Claudin-11 plays a vital role in the central nervous system, contributing to blood-brain barrier formation, a selective barrier protecting the brain from harmful substances while allowing essential nutrients to pass through. Claudin-11′s unique structure, including four transmembrane domains and two extracellular loops, facilitates tight junction strand formation that seals intercellular space. |
| Product Image Gallery | |
 Western blot analysis of extracts on Mouse kidney cells, using Claudin-11 Rabbit Polyclonal Antibody (EAB11244) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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