| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF/ICC, ELISA | 134 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IHC-P=1:50-300 IF/ICC=1:50-300 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Jagged1 Rabbit Polyclonal Antibody detects endogenous levels of Jagged1 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Jagged1 also known as JAG1, CD339 is a type I membrane-anchored multidomain protein and a ligand of the Notch receptor. Jagged1 plays a crucial role in the Notch signaling pathway, which is essential for various developmental processes, including cell fate determination and tissue differentiation. Specifically, Jagged1 acts as a ligand for Notch receptors, facilitating communication between adjacent cells and influencing developmental pathways. This interaction is particularly important in cardiovascular development and hematopoiesis, where Jagged1 helps regulate the balance between cell proliferation and differentiation. |
| Product Image Gallery | |
 Western blot analysis of extracts on DU145, PC3 cells, using Jagged1 Rabbit Polyclonal Antibody (EAB13161) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
Predicted band size: 134 kDa; Observed band size: 140 kDa  Immunohistochemical analysis of paraffin-embedded Mouse kidney tissue, using Jagged1 Rabbit Polyclonal Antibody (EAB13161) at 1:100 dilution.
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