| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IP, IF/ICC | 31 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:1000-5000 IP=1:10-100 IF/ICC=1:100-500 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | IL-1β Rabbit Monoclonal Antibody detects endogenous levels of IL-1β protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
IL-1β also known as IL1F2, IL-1 beta, interleukin 1 beta, IL1B is a member of the interleukin 1 cytokine family. IL-1β plays a pivotal role in the immune response and inflammation, acting as a key mediator that influences the activity of T and B lymphocytes as well as natural killer (NK) cells. Notably, IL-1β is produced in response to inflammatory stimuli and is crucial for the activation of immune cells, promoting the secretion of other cytokines such as IL-2 while inhibiting IL-4 expression in T cells. This regulatory function is essential for maintaining a balanced immune response, and dysregulation of IL-1β has been linked to various pathological conditions, including rheumatoid arthritis and inflammatory bowel disease. The ability of IL-1β to induce B cell proliferation and immunoglobulin synthesis further underscores its importance in adaptive immunity. |
| Product Image Gallery | |
 Western blot analysis of extracts on 293T, Mouse brain cells, using IL-1β Rabbit Monoclonal Antibody (EAB21516) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
Predicted band size: 31 kDa; Observed band size: 17,31 kDa |
