| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IF/ICC, ELISA | 54 | Human, Mouse |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IF/ICC=1:50-300 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Pea3/ETV4 Rabbit Polyclonal Antibody detects endogenous levels of Pea3/ETV4 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
ETV4 also known as Pea3 is a member of the Ets gene family. ETV4 plays a crucial role in regulating gene expression during development and cellular differentiation, particularly in epithelial and fibroblastic cells. ETV4′s ability to bind specific DNA motifs, such as the ETV4 motif (5′-AGGAAG-3′), allows ETV4 to influence the transcription of target genes, which is vital for processes like cell proliferation and migration. Notably, ETV4 is not expressed in hematopoietic cells, distinguishing ETV4 from other Ets family members like Ets-1 and Ets-2, which are primarily found in blood cell lineages. This specificity in expression highlights the unique functional roles of Ets proteins in different cell types and developmental contexts, making ETV4 a significant marker for studying epithelial and fibroblast biology. |
| Product Image Gallery | |
 Western blot analysis of extracts on SKOV3,SW480, Raji, Mouse heart cells, using Pea3/ETV4 Rabbit Polyclonal Antibody (EAB13010) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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