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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, ELISA | 113 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 IHC-P=1:50-300 |
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| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | PGC1β Rabbit Polyclonal Antibody detects endogenous levels of PGC1β protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
PGC1β also known as PERC, PPARGC1B plays a crucial role as a transcriptional coactivator that regulates mitochondrial biogenesis and energy metabolism. PGC1β interacts with key transcription factors such as nuclear respiratory factor-1 (NRF-1), estrogen receptor alpha (ERα), and glucocorticoid receptor (GR), thereby influencing processes like energy expenditure and glucose metabolism. PGC1β is predominantly expressed in tissues with high metabolic activity, including the brain, heart, and skeletal muscle, and expression is modulated by insulin and fatty acids. Notably, PGC1β undergoes post-translational modifications, including phosphorylation and acetylation, which can significantly impact activity and stability, thereby affecting metabolic pathways and potentially contributing to metabolic disorders such as obesity. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela cells, using PGC1β Rabbit Polyclonal Antibody (EAB11807) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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