DBP Rabbit Polyclonal Antibody
Catalog #:EAB11819
Host / Isotype Clonality Applications MW (kDa) Reactivity
Rabbit IgG Polyclonal WB, ELISA 53 Human, Monkey
Application Key

WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry

Reactivity Key

H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Applications Dilutions
The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user.
WB(Westem Blotting)
IHC-P(Immunohistochemistry-Paraffin)
IF/ICC(Immunofluorescence/Immunocytochemistry)
ELISA(Enzyme-linked Immunosorbent Assay)
WB=1:500-2000
Product Information
Conjugate Unconjugate
Specificity DBP Rabbit Polyclonal Antibody detects endogenous levels of DBP protein.
Purification Affinity purification
Concentration 1mg/ml
Format Liquid
Formulation In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping Gel Pack
Storage Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
UniProt ID

P02774

Entrez Gene ID

2638

Product Description

DBP(Vitamin D-binding protein) also known as GC is a member of the albumin gene family. DBP plays a crucial role in transporting vitamin D and its metabolites to target organs within the vitamin D endocrine system, essential for maintaining calcium homeostasis and bone health. DBP exhibits immunomodulatory properties, binding to leukocyte surfaces and enhancing immune responses. DBP is located in the extracellular space, primarily in the serum, where DBP interacts with various cell types, facilitating diverse cellular functions. DBP binds to chondroitin sulfate proteoglycans on cell membranes, which is vital for cell signaling and immune response modulation. DBP serves as a co-chemotactic factor for C5a, enhancing chemotactic activity, and has a high-affinity interaction with globular actin, contributing to actin clearance from the bloodstream. 

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For Research Use Only, Not For Diagnostic Or Therapeutic Procedures.
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