| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Mouse IgG2b | Monoclonal | WB, IP, IHC-P, IF/ICC, ELISA | 23 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:2000-10000 IP=1:100-500 IHC-P=1:200-1000 IF/ICC=1:100-500 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | SNAP25 Mouse Monoclonal Antibody detects endogenous levels of SNAP25 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
SNAP25 is a critical component of the SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor) complex, which plays a vital role in the process of neurotransmitter release at synapses. SNAP25 is primarily located in the presynaptic membrane of neurons, where SNAP25 facilitates the fusion of synaptic vesicles with the plasma membrane, allowing for the efficient release of neurotransmitters into the synaptic cleft. Proper functioning of SNAP25 is essential for synaptic transmission and communication between neurons, making SNAP25 a key player in various neurological processes. Dysregulation of SNAP25 has been implicated in several neurological disorders, including schizophrenia and autism spectrum disorders, highlighting SNAP25′s importance in maintaining synaptic health and function. |
| Product Image Gallery | |
 Western blot analysis of extracts on HEK293, PC12, Mouse brain, Rat brain cells, using SNAP25 Mouse Monoclonal Antibody (EAB22271) at 1:5000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution.
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