| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Mouse IgG1 | Monoclonal | WB, IHC-P, IF/ICC, ELISA | 58 | Human, Monkey |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IHC-P=1:100-500 IF/ICC=1:100-500 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | PAK2 Rabbit Monoclonal Antibody detects endogenous levels of PAK2 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
PAK2 also known as γPAK, PAKγ is a serine/threonine kinase that plays a crucial role in cellular signaling pathways, particularly in regulating the JNK signaling cascade. PAK2 is located in the cytoplasm and interacts with active forms of Rac1 and Cdc42, which are small GTPases involved in various cellular processes, including cytoskeletal reorganization and cell migration. PAK2 interaction with these GTPases leads to phosphorylation of downstream substrates, such as MEK kinase, which subsequently activates the JNK pathway. This pathway is vital for cellular responses to stress and apoptosis, highlighting PAK2′s importance in maintaining cellular homeostasis and responding to external stimuli. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, Jurkat, K562 cells, using PAK2 Mouse Monoclonal Antibody (EAB22115) at 1:1000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution.
Predicted band size: 58 kDa; Observed band size: 61 kDa |
