hnRNP E2 Rabbit Polyclonal Antibody
Catalog #:EAB14945
Host / Isotype Clonality Applications MW (kDa) Reactivity
Rabbit IgG Polyclonal WB, ELISA 40 Human, Mouse
Applications Dilutions
The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user.
WB=1:500-2000
Application Key

WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry

Reactivity Key

H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Information
Conjugate Unconjugate
Specificity hnRNP E2 Rabbit Polyclonal Antibody detects endogenous levels of hnRNP E2 protein.
Purification Affinity purification
Concentration 1mg/ml
Format Liquid
Formulation In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping Gel Pack
Storage Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
UniProt ID

Q15366

Entrez Gene ID

5094

Product Description

hnRNP E2 also known as PCBP2 is a member of the heterogeneous nuclear ribonucleoprotein family. hnRNP E2 plays a crucial role in mRNA metabolism, including transcription, pre-mRNA processing, and mature mRNA transport to the cytoplasm for translation. hnRNP E2 is primarily localized in the nucleus, where hnRNP E2 associates with heterogeneous nuclear RNA (hnRNA) produced by RNA polymerase II, and is essential for spliceosomal complex formation. hnRNP E2 stabilizes mRNA, which enhances polioviral mRNA translation, influencing viral replication. hnRNP E2 also interacts with other proteins such as hnRNP M, implicated in pre-mRNA splicing and stress-induced splicing regulation. 

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For Research Use Only, Not For Diagnostic Or Therapeutic Procedures.
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