| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF/ICC, ELISA | 32 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IHC-P=1:50-300 IF/ICC=1:50-300 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | PD-L2 Rabbit Polyclonal Antibody detects endogenous levels of PD-L2 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
PD-L2 also known as CD273, B7DC, Pdcd-1L2 is a 73 amino acid type I transmembrane protein that plays a crucial role in the immune system by providing inhibitory signals to T cells, thereby regulating immune responses and maintaining tolerance. Pdcd-1L2′s structure includes a signal sequence, immunoglobulin V-like and C-like domains, a transmembrane region, and a cytoplasmic region, which are essential for mediating interactions with immune receptors. The gene encoding Pdcd-1L2 is located on human chromosome 9p24.2, and Pdcd-1L2 expression on various parenchymal cells, such as those in the heart, lung, and kidney, suggests that the Pdcd-1-Pdcd-L system may be pivotal in preventing autoimmune diseases by modulating T cell activity. Pdcd-1L2′s ability to interact with other proteins in the immune system further underscores its importance in maintaining immune homeostasis and preventing excessive immune responses. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela cells, using PD-L2 Rabbit Polyclonal Antibody (EAB11840) at 1:2000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
 Immunohistochemical analysis of paraffin-embedded Human liver tissue, using PD-L2 Rabbit Polyclonal Antibody (EAB11840) at 1:100 dilution.
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