| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Monoclonal | WB, IHC-P, IF/ICC, FC | 120 | Human |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IHC-P=1:50-200 IF/ICC=1:50-200 FC=1:10-100 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | PELP1 Rabbit Monoclonal Antibody detects endogenous levels of PELP1 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
PELP1 also known as MNAR, P160 is a transcription factor which coactivates transcription of estrogen receptor responsive genes and corepresses genes activated by other hormone receptors or sequence-specific transcription factors. PELP1 plays a critical role in modulating estrogen receptor activity, which is vital for understanding cancer progression, particularly in endometrial cancers. PELP1 is primarily located in the cytoplasm of cells, where PELP1 interacts with estrogen receptors and other nuclear hormone receptors, influencing their transcriptional activity. This subcellular localization allows PELP1 to participate in both genomic and non-genomic signaling pathways, thereby affecting cellular proliferation and differentiation. PELP1′s expression is often deregulated in endometrial tumors, highlighting PELP1′s potential as a biomarker for cancer diagnosis and prognosis. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, Jurkat cells, using PELP1 Rabbit Monoclonal Antibody (EAB22124) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
Predicted band size: 120 kDa; Observed band size: 160 kDa |
