| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IP, IHC-P, IF, ELISA | 28 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IP=1:20-200 IHC-P=1:50-300 IF=1:50-300 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Prdx3 Rabbit Polyclonal Antibody detects endogenous levels of Prdx3 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Prdex3(Peroxiredoxin 3) also known as PRX III is a mitochondrial protein with antioxidant function. Prdex3 plays a crucial role in cellular defense against oxidative stress by reducing reactive oxygen species (ROS) and maintaining redox homeostasis. Prdex3′s localization within the mitochondria is particularly significant, as this organelle is a major site of ROS production during cellular respiration. By effectively neutralizing ROS in the mitochondria, Prdex3 helps to prevent oxidative damage to mitochondrial DNA and proteins, which is vital for maintaining mitochondrial function and overall cellular health. Dysregulation of Prdex3 has been implicated in various diseases, including cancer and neurodegenerative disorders, highlighting Prdex3′s importance in both normal physiology and disease pathology. Prdex3 expression is notably elevated in certain cancers, suggesting a potential role in tumorigenesis and progression. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, HepG2, A549 cells, using Prdx3 Rabbit Polyclonal Antibody (EAB11837) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
 Immunohistochemical analysis of paraffin-embedded Human lung carcinoma tissue, using Prdx3 Rabbit Polyclonal Antibody (EAB11837) at 1:100 dilution.
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