| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Mouse IgG1 | Monoclonal | WB, IHC-P, IF/ICC, ELISA | 22 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:5000-20000 IHC-P=1:500-2000 IF/ICC=1:200-1000 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Prdx2 Mouse Monoclonal Antibody detects endogenous levels of Prdx2 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Prdx2 also knonw as PRXII is a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. Prdx2 plays a crucial role in cellular defense against oxidative stress by reducing reactive oxygen species (ROS), thereby protecting cells from damage that can lead to various diseases, including cancer and neurodegenerative disorders. Prdx2 is primarily localized in the cytoplasm and is known to interact with thioredoxin, which serves as its electron donor during the antioxidation process. Prdx2′s cytoplasmic localization enables rapid response to oxidative stress, allowing for efficient detoxification of ROS in the cellular environment. Prdx2 is overexpressed in certain cancers, such as breast cancer, indicating its potential role in tumorigenesis and progression. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, HepG2, PC12 cells, using Prdx2 Mouse Monoclonal Antibody (EAB22033) at 1:10000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution.
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