| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Monoclonal | WB, IF/ICC | 67 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IF/ICC=1:50-200 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Rev-Erbα Rabbit Monoclonal Antibody detects endogenous levels of Rev-Erbα protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Rev-erbα also known as NR1D1 is a transcription factor. Rev-erbα plays a crucial role in regulating circadian rhythms and metabolic processes by acting as a transcriptional repressor. Rev-erbα is primarily located in the nucleus, where Rev-erbα binds to specific DNA sequences to modulate gene expression. Nuclear localization enables Rev-erbα to interact with other nuclear proteins and transcription factors, thereby influencing the expression of genes involved in circadian rhythm regulation and lipid metabolism. Rev-erbα interacts with co-activator NCOA5, which enhances transcriptional activity, highlighting Rev-erbα′s importance in the intricate network of gene regulation. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, MCF7, Jurkat cells, using Rev-Erbα Rabbit Monoclonal Antibody (EAB22032) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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