| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Monoclonal | WB, IP, IF/ICC | 47 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:1000-5000 IP=1:10-100 IF/ICC=1:100-500 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | MAPKAPK-2 Rabbit Monoclonal Antibody detects endogenous levels of MAPKAPK-2 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
MAPKAPK-2 also known as MK2 a member of the Ser/Thr protein kinase family. MAPKAPK-2 plays a crucial role in cellular signaling pathways, particularly in response to stress and inflammatory stimuli, by acting as a downstream effector of p38 MAP kinase and extracellular signal-regulated kinase (ERK) pathways. MAPKAPK-2 is primarily located in the cytoplasm and translocates to the nucleus upon activation, where MAPKAPK-2 regulates gene expression and cell survival. MAPKAPK-2′s ability to modulate these pathways is vital for processes such as cell proliferation, differentiation, and apoptosis, making MAPKAPK-2 an important target for research in cancer and other diseases. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, Raw264.7 cells, using MAPKAPK-2 Rabbit Monoclonal Antibody (EAB22138) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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