| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Monoclonal | WB, IP, IHC-P, IF/ICC | 56 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:1000-5000 IP=1:10-100 IHC-P=1:100-500 IF/ICC=1:100-500 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | MST1 Rabbit Polyclonal Antibody detects endogenous levels of MST1 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
MST1 also known as KRS2, STK4 is a member of the mammalian Ste20-like kinase family, which plays a crucial role in cellular signaling pathways that regulate cell growth, survival, and apoptosis. MST1 is primarily located in the cytoplasm and can translocate to the nucleus under certain conditions, which is significant for its function in mediating stress responses and promoting cell survival. MST1 is known to interact with various signaling molecules, including caspase-3, which MST1 activates, thereby influencing apoptotic pathways. MST1′s ability to phosphorylate substrates and itself is essential for regulatory functions in the MAPK signaling cascade, making MST1 a vital component in the cellular response to external stimuli. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, NIH/3T3 cells, using MST1 Rabbit Monoclonal Antibody (EAB22132) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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