| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Mouse IgG1 | Monoclonal | WB, IHC-P, IF/ICC, ELISA | 52 | Human |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IHC-P=1:100-500 IF/ICC=1:100-500 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | IRF-4 Mouse Monoclonal Antibody detects endogenous levels of IRF-4 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
IRF-4 also known as MUM1 is a member of the IRF family of DNA-binding factors, which plays a crucial role in the immune system as a transcriptional activator that regulates the expression of genes involved in immune responses, particularly in lymphoid cells. IRF-4 is essential for the differentiation of T helper 2 cells and the development of plasma cells, which are vital for antibody production. IRF-4′s ability to bind to the interferon-stimulated response element (ISRE) of the major histocompatibility complex (MHC) class I promoter underscores IRF-4′s importance in modulating immune responses and maintaining immune homeostasis. Additionally, IRF-4 interacts with other proteins, such as PU.1, which further highlights IRF-4′s role in the regulation of gene expression within the immune system. |
| Product Image Gallery | |
 Western blot analysis of extracts on Daudi cells, using IRF-4 Mouse Monoclonal Antibody (EAB22007) at 1:1000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution.
 Immunohistochemical analysis of paraffin-embedded Human colon tissue, using IRF-4 Mouse Monoclonal Antibody (EAB22007) at 1:200 dilution.
 Immunohistochemical analysis of paraffin-embedded Human tonsil tissue, using IRF-4 Mouse Monoclonal Antibody (EAB22007) at 1:200 dilution.
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