| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Monoclonal | WB, IHC-P, IF/ICC | 69 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | LTA4H Rabbit Monoclonal Antibody detects endogenous levels of LTA4H protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
LTA4H also known as LKHA4 is an enzyme that contains both hydrolase and aminopeptidase activities. plays a crucial role in the metabolism of leukotrienes, which are bioactive lipids derived from arachidonic acid that are essential for mediating inflammatory responses and host defense mechanisms. Located primarily in the cytosol, LTA4H is a zinc-dependent enzyme that exhibits both epoxide hydrolase and aminopeptidase activities. LTA4H epoxide hydrolase function is particularly significant as LTA4H catalyzes the conversion of leukotriene A4 to leukotriene B4, a potent lipid mediator that acts as a chemoattractant, guiding immune cells to sites of inflammation and infection. LTA4H aminopeptidase activity further contributes to regulatory role in immune responses by processing peptide substrates. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, K562, C6 cells, using LTA4H Rabbit Monoclonal Antibody (EAB21982) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
|
