| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IP, IHC-P, IF/ICC | 74 | Human |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IHC-P=1:50-200 IF/ICC=1:50-200 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | KIFC1 Rabbit Monoclonal Antibody detects endogenous levels of KIFC1 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
KIFC1(Kinesin family member C1) also known as HSET, KNSL2 is a 673 amino acid protein that plays a pivotal role in organizing microtubules during cell division. KIFC1 is primarily located in the nucleus and features a C-terminal kinesin-motor domain, which is essential for function as a minus-end directed microtubule-dependent motor. KIFC1 interacts with NuMA and cytoplasmic Dynein to facilitate the organization of microtubule minus ends at spindle poles, a critical process for ensuring proper bipolar spindle formation. Disruption of KIFC1 function in HeLa cells leads to the formation of multipolar mitotic spindles, highlighting importance in maintaining the fidelity of cell division. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, MCF7, SH-SY5Y cells, using KIFC1 Rabbit Monoclonal Antibody (EAB22107) at 1:2000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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