| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IF/ICC, ELISA | 95 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IF/ICC=1:50-300 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | NF90/ILF3 Rabbit Polyclonal Antibody detects endogenous levels of NF90/ILF3 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
NF90 also known as ILF3 is a crucial nuclear protein that plays a significant role in the regulation of gene expression, particularly in T-cells. NF90 exists as a heterodimer with NF45 and contains two double-stranded RNA-binding domains and one DZF domain, which are essential for binding to RNA and regulating the expression of interleukin-2 by interacting with the antigen receptor response element of the IL-2 enhancer. NF90′s structure enables interactions with double-stranded RNA, which is vital for immune response and viral defense mechanisms. NF90 also represses the replication of certain viruses, such as human rhinovirus type 2, by binding to specific regions of viral RNA, showcasing a role in both cellular regulation and antiviral responses. |
| Product Image Gallery | |
 Western blot analysis of extracts on A549, K562, NIH/3T3 cells, using NF90/ILF3 Rabbit Polyclonal Antibody (EAB11788) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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