| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Monoclonal | WB, IHC-P, IF/ICC | 55 | Human, Monkey |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IHC-P=1:100-500 IF/ICC=1:100-500 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | HDAC1 Rabbit Monoclonal Antibody detects endogenous levels of HDAC1 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
HDAC1(Histone deacetylase 1) also known as GON-10, HD1, KDAC1, RPD3, RPD3L1 is a member of the histone deacetylase family. HDAC1 plays a pivotal role in the regulation of gene expression by modulating chromatin structure through the removal of acetyl groups from lysine residues on histone proteins, leading to chromatin condensation and transcriptional repression. This enzymatic activity is essential for processes such as cell cycle progression, differentiation, and development. HDAC1 is involved in maintaining genomic stability and regulating various signaling pathways. Dysregulation of HDAC1 has been implicated in numerous diseases, including cancer, neurological disorders, and inflammatory conditions, making HDAC1 a critical target for therapeutic intervention and a key focus in epigenetic research. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, K562 cells, using HDAC1 Rabbit Monoclonal Antibody (EAB22030) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
Predicted band size: 55 kDa; Observed band size: 62 kDa |
