| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF/ICC, ELISA | 70 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IHC-P=1:50-300 IF/ICC=1:50-300 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | hnRNP Q Rabbit Polyclonal Antibody detects endogenous levels of hnRNP Q protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
hnRNP Q also known as HNRNPQ, SYNCRIP is a member of the cellular heterogeneous nuclear ribonucleoprotein (hnRNP) family. hnRNP Q plays a pivotal role in RNA processing, particularly in regulating pre-mRNA splicing, which is essential for proper gene expression. hnRNP Q is widely expressed across different tissues and is developmentally regulated, highlighting its importance in various biological processes. hnRNP Q interacts with several key proteins, including survival motor neuron protein (SMN), which is crucial for motor neuron health. Disruption of hnRNP Q and SMN interaction due to genetic mutations can lead to spinal muscular atrophy, a severe neurodegenerative disorder. Additionally, hnRNP Q exhibits a unique expression pattern, being upregulated after midnight, which correlates with a decline in AANAT, the enzyme responsible for melatonin synthesis. |
| Product Image Gallery | |
 Western blot analysis of extracts on HuvEc, Jurkat, SH-SY5Y, HT29 cells, using hnRNP Q Rabbit Polyclonal Antibody (EAB11776) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
Predicted band size: 70 kDa; Observed band size: 62 kDa  Immunohistochemical analysis of paraffin-embedded Human breast cancer tissue, using hnRNP Q Rabbit Polyclonal Antibody (EAB11776) at 1:200 dilution.
 Immunofluorescence analysis of HepG2 cell, using hnRNP Q Rabbit Polyclonal Antibody (EAB11776) at 1:200 dilution.
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