| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Mouse IgG2b | Monoclonal | WB, IHC-P, IF/ICC, ELISA | 43 | Human |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IHC-P=1:100-500 IF/ICC=1:100-500 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | GATA-1 Mouse Monoclonal Antibody detects endogenous levels of GATA-1 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
GATA-1 is a member of the GATA family. GATA-1 is essential for transcriptional regulation of erythroid-specific genes, thereby influencing red blood cell development. GATA-1 function is vital for proper hematopoiesis, and dysregulation of GATA-1 can lead to various blood disorders, including anemia and other erythroid lineage-related diseases. GATA-1 is characterized by a conserved zinc finger DNA-binding domain that allows binding to the WGATAR consensus sequence, which is critical for gene regulation. GATA-1 interacts with other GATA family members, such as GATA-2 and GATA-3, which have broader regulatory capabilities, indicating a complex network of transcriptional control within the hematopoietic system. |
| Product Image Gallery | |
 Western blot analysis of extracts on K562 cells, using GATA-1 Mouse Monoclonal Antibody (EAB22049) at 1:1000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution.
 Immunohistochemical analysis of paraffin-embedded Human pancreatic cancer tissue, using GATA-1 Mouse Monoclonal Antibody (EAB22049) at 1:400 dilution.
 Immunofluorescence analysis of K562 cell, using GATA-1 Mouse Monoclonal Antibody (EAB22049) at 1:400 dilution.
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