| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Mouse IgG1 | Monoclonal | WB, IF/ICC, FC, ELISA | 38 | Human |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IF/ICC=1:100-500 FC=1:50-200 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | FAS Mouse Monoclonal Antibody detects endogenous levels of FAS protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
FAS also known as CD95, TNFRSF6 is a member of the TNF-receptor superfamily. FAS plays a crucial role in regulating apoptosis, which is the process of programmed cell death that is essential for maintaining cellular homeostasis and immune system function. FAS mediates apoptosis to eliminate virus-infected or transformed cells, thereby contributing to the body′s defense mechanisms against malignancies and infections. FAS is a cell surface glycoprotein that belongs to a receptor family that includes CD40 and tumor necrosis factor receptors, and is expressed on a wide range of lymphoid cell lines. FAS interaction with FAS-L is vital for triggering the apoptotic signaling cascade, highlighting the importance of this pathway in immune responses. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, Jurkat cells, using FAS Mouse Monoclonal Antibody (EAB21949) at 1:1000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution.
Predicted band size: 38 kDa; Observed band size: 40-60 kDa |
