| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Monoclonal | WB, IHC-P, IF/ICC | 49 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:1000-5000 IHC-P=1:100-500 IF/ICC=1:100-500 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | HNF3α/FoxA1 Rabbit Monoclonal Antibody detects endogenous levels of HNF3α/FoxA1 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
HNF3α also known as FOXA1 is a member of the forkhead class of DNA-binding proteins. plays a crucial role in regulating gene expression in the liver and other tissues, and proves essential for proper development of the endoderm during embryogenesis. HNF3α is involved in transcriptional regulation of genes vital for liver function, including those responsible for glucose metabolism and lipid homeostasis. HNF-3α′s ability to interact with other members of the hepatocyte nuclear factor family, such as HNF1 and HNF4, underscores its importance in maintaining metabolic processes and cellular differentiation. HNF3α has been implicated in regulating genes involved in body axis formation during gastrulation, highlighting a multifaceted role in development and metabolism. |
| Product Image Gallery | |
 Western blot analysis of extracts on MCF7, HepG2, 4T1 cells, using HNF3α/FoxA1 Rabbit Monoclonal Antibody (EAB21948) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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